CENTER FOR CANCER RESEARCH
Synthesis and biological evaluation of benzomorpholine derivatives as novel EZH2 inhibitors for anti-non-small cell lung cancer activity | SpringerLink
High-throughput screening with nucleosome substrate identifies small-molecule inhibitors of the human histone lysine methyltransferase NSD2 - ScienceDirect
Synthesis and biological evaluation of benzomorpholine derivatives as novel EZH2 inhibitors for anti-non-small cell lung cancer activity | SpringerLink
Vulnerabilities of Mutant SWI/SNF Complexes in Cancer: Cancer Cell
IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in Chromatin Remodeling and Disease Development
Design, synthesis and biological evaluation of novel 1-methyl-3-oxo-2,3,5,6,7,8-hexahydroisoquinolins as potential EZH2 inhibitors - RSC Advances (RSC Publishing) DOI:10.1039/C5RA02365C
IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in Chromatin Remodeling and Disease Development
IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in Chromatin Remodeling and Disease Development
Transcriptional Regulation and Its Misregulation in Disease: Cell
Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma - ScienceDirect
Cancer-epigenetic function of the histone methyltransferase KMT2D and therapeutic opportunities for the treatment of KMT2D-deficient tumors | Oncotarget
Synthesis and biological evaluation of benzomorpholine derivatives as novel EZH2 inhibitors for anti-non-small cell lung cancer activity | SpringerLink
PDF) Targeting Histone Lysine Methylation in Cancer
High-throughput screening with nucleosome substrate identifies small-molecule inhibitors of the human histone lysine methyltransferase NSD2 - Journal of Biological Chemistry
An Alternative Approach to ChIP-Seq Normalization Enables Detection of Genome-Wide Changes in Histone H3 Lysine 27 Trimethylation upon EZH2 Inhibition | PLOS ONE
Role of somatic cancer mutations in human protein lysine methyltransferases - ScienceDirect
KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer - ScienceDirect
IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in Chromatin Remodeling and Disease Development
Histone methylation modifiers in medical therapeutics - ScienceDirect
berry (@berry46566269) / Twitter
Full article: Epigenetic modification in chromatin machinery and its deregulation in pediatric brain tumors: Insight into epigenetic therapies
KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer
